M PROTEIN TYPING OF THAI GROUP A STREPTOCOCCAL ISOLATES BY PCR-RESTRICTION FRAGMENT LENGTH POLYMORPHISM ANALYSIS

M protein typing of Thai group A streptococcal isolates by PCR-Restriction fragment length polymorphism analysis

Abstract Background Group A streptococcal (GAS) infections can lead to the development of severe post-infectious sequelae, such as rheumatic fever (RF) and rheumatic heart disease (RHD).RF and RHD are a major health concern in developing countries, and in indigenous populations of developed nations.The majority of GAS isolates are M protein-nontype

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Osthole ameliorates wear particle-induced osteogenic impairment by mitigating endoplasmic reticulum stress via PERK signaling cascade

Abstract Background Periprosthetic osteolysis and subsequent aseptic loosening are the leading causes of failure following total joint arthroplasty.Osteogenic impairment induced by wear particles is regarded as a crucial contributing factor in the development of osteolysis, with endoplasmic reticulum (ER) stress identified as a key underlying mecha

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